Production of high-end wet mixing granulator to meet pharmaceutical production process needs

With the adjustment of the medical insurance catalogue, the introduction of the negotiation catalogue, the gradual landing of bidding, etc., the recovery of China's pharmaceutical industry in 2017, the overall growth rate of some listed pharmaceutical companies has steadily increased. The pharmaceutical market is performing well, so as a tool for pharmaceutical production, it is necessary to grasp the opportunity to improve the overall "quality" of the equipment to meet the needs of the pharmaceutical market. At the same time, China's pharmaceutical industry wants to become a pharmaceutical powerhouse and cannot do without the support of advanced equipment. In order to promote the development of the pharmaceutical industry, it is also for the sound development of China's pharmaceutical equipment, pharmaceutical companies still need to work hard, pick up their sleeves and add fuel.

In the pharmaceutical production process, pharmaceutical equipment is directly in contact with pharmaceuticals, semi-finished products and raw materials. If the pharmaceutical equipment does not meet the requirements, it will directly cause errors and pollution in the production of the medicine. Therefore, pharmaceutical equipment should be produced in strict accordance with GMP requirements. Experts said that pharmaceutical equipment must not only meet the production process requirements, but also can not contaminate drugs and production environment, and is conducive to online cleaning, disinfection, sterilization and so on.

In the pharmaceutical production process, whether pharmaceutical equipment meets GMP requirements will directly affect the quality of GMP implemented by pharmaceutical companies. Therefore, pharmaceutical equipment companies need to strictly comply with GMP requirements, not only that, but with the advent of the pharmaceutical industry 4.0 era, pharmaceutical companies have put forward higher requirements for equipment. In order to achieve transformation and upgrading, the pharmaceutical industry must improve product quality and production efficiency, and promote the industry to enter the middle and high-end direction. In order to meet the needs of pharmaceutical production processes, the pharmaceutical equipment industry also needs to advance to the middle and high end.

With the introduction of the "Made in China 2025" plan, China's pharmaceutical machinery and equipment industry is also fully entering the stage of transformation and upgrading. Many enterprises have begun to take the "intelligence" route, such as Chutian Technology, Qianshan Pharmaceutical Machinery and other large domestic enterprises are in the smart A certain achievement has been made in the field of medicine machines. With the advancement of science and technology and the transformation and upgrading of intellectual development, China has also begun to emerge a number of advanced pharmaceutical equipment products.

Taking the high-efficiency wet mixing granulator as an example, the products introduced by Zhejiang Tomorrow Machinery Co., Ltd. introduced human-machine interface and PLC control technology, which made the granulated product particles firm, uniform in particle size and high in yield. “The efficiency of this product is 4-5 times that of ordinary granulator, and the noise is low, which meets the requirements of GMP production,” the relevant staff said.

Nowadays, China's pharmaceutical equipment industry is getting farther and farther in the middle and high-end routes, and better meets the needs of pharmaceutical production processes. However, from the current point of view, China's pharmaceutical equipment still has many shortcomings in terms of technology. For example, in the production of pharmaceuticals, most of the production equipment and processes are isolated, and many links are still artificial. There is still a long way to go in the automation of pharmaceutical equipment. In addition, some insiders said that there are still many pharmaceutical equipments in China that do not have complete data output functions of important quality parameters and process condition parameters. In short, in the high-end route, China's pharmaceutical equipment industry needs to be full of strength. No cross-contamination, no pollution to the environment, the pharmaceutical equipment industry still needs to "refuel"

The inability to contaminate drugs and the production environment is another important requirement for pharmaceutical companies in the pharmaceutical equipment industry. It is understood that if cross-contamination occurs in the pharmaceutical production process, this will not only seriously affect the quality and efficacy of the drug, but also cause great harm to the production personnel and the ecological environment. Therefore, prevention of cross-contamination has a deeper level for pharmaceuticals. significance.

According to the relevant technical personnel, the pollution prevention and control of pharmaceutical equipment in the pharmaceutical production process mainly includes that the equipment itself does not pollute drugs and the environment and the pharmaceutical equipment has strong prevention and control means. In order to improve the quality of pharmaceuticals and protect the ecological environment, the pharmaceutical equipment industry needs to start from the details in the design process, taking into account many factors. For example, pharmaceutical equipment enterprises must strictly control the material selection of equipment during the production process, so that parts that are in direct contact with the drug are non-toxic, non-corrosive, do not produce chemical reactions, and do not release the release of particles; Fully consider the factors of cleaning, disinfection, sterilization, etc., to ensure that the equipment has no dead angle, easy to clean, and will not cause the last remnant to affect the next pharmaceutical production.

The excellent process of pharmaceutical equipment is one of the important aspects to ensure the quality of medicines. At the same time, if the pharmaceutical equipment fully considers the environmental pollution and other issues in the design and production process, it can achieve zero discharge or prevent dust, leak, heat and noise. Then, the problem of pharmaceutical environmental pollution will also be greatly reduced.

Nowadays, the state has put forward higher requirements for green pharmaceutical production. Various environmental protection measures have pointed out pharmaceutical companies such as APIs, and some pharmaceutical companies will face a pattern of production suspension, elimination and reshuffle. Faced with environmental pressures, pharmaceutical equipment companies should think about the issue from the perspective of energy conservation and environmental protection, and can no longer seek industry development at the expense of the environment. Experts said that in order to promote more energy-saving and environmental protection of pharmaceutical equipment, pharmaceutical companies can prevent and control pollution in terms of functions, appearance structure, material selection, and equipment verification.

Nowadays, China has become the second largest pharmaceutical market, and the demand for the pharmaceutical market is increasing day by day. With the growth of the pharmaceutical market, China has put forward higher requirements for pharmaceutical quality. In addition, the environmental protection policy has repeatedly exerted its strength on the pharmaceutical industry. For example, the recent 10 ministries and commissions, together with Beijing, Tianjin, Hebei and other six provinces (cities) issued the “Beijing-Tianjin-Hebei and surrounding areas in the autumn and winter of 2017-2018 comprehensive measures to tackle the air pollution,” It is emphasized that the raw material drug manufacturers should stop production in violation of the emission process. Faced with the strengthening of the flight inspection, the improvement of pharmaceutical quality requirements, the tightening of environmental protection policies, and the unprecedented pressure of pharmaceutical pressure, the pharmaceutical equipment industry has only spurred enough strength to set up sleeves to refuel and produce high-tech content, high quality, energy saving and environmental protection. Equipment can help pharmaceutical companies escape the “life and death” and get rid of the anxiety of being eliminated. At the same time, pharmaceutical equipment companies can only ensure their own development and achieve long-term sustainable development.